The opposite or antonyms for the word "more rejuvenated" would be "less refreshed," "more fatigued," "weaker," "fatigued," "worn-out," "exhausted," "lethargic," and "drained." These words describe a state of being tired, weak, and lacking in energy or vitality. When on the opposite side of being rejuvenated, one's ability to perform tasks, concentrate and deal with stress can become difficult. It is important to maintain good health, sleep, and regular exercise to keep oneself rejuvenated and energetic. By doing so, it keeps you more focused and productive in your day-to-day.