Took one's life in one's hands is a common idiom used to express a dangerous or risky decision. However, if you're looking for synonyms for this phrase, you can use the following: risked everything, braved fate, faced the unknown, courted danger, dared all, gambled with one's life, ventured into the abyss, leapt into uncertainty, challenged fate, gambled one's future, and played a dangerous game. These phrases convey the same meaning as taking one's life in one's hands and help to add more variety and interest to your writing or conversations. Whether you choose to use the original phrase or any of its associated synonyms, it's important to use them appropriately and with the necessary context.